If you're unfamiliar with the most abundant enzyme on Earth, Rubisco, (upon which essentially all plant and animal life is totally dependent), you might wish to read this. For those who are curious about life, the universe and everything. What is truly amazing is that a long, LONG time ago, nature came up with an OK, but not great, way to fix carbon into the very stuff of life, but it was before there was a lot of oxygen in the atmosphere, so it's not quite good enough at distinguishing CO2 from Oxygen. But humans, whose adaptive intelligence is THE most significant development since the evolution of photosynthesis, are about to dramatically improve the efficiency of Rubisco, after 3½ billion years, by modifying its natural form to make it better at rejecting oxygen and latching on to CO2, which is its function.
24 February 2021
Rubisco, Evolution, and the implications of rational intervention in the future of life
01 February 2021
A Humble Request
23 January 2021
What if....?
11 January 2021
Truly excellent presentation by physicist Sean Carroll on the predicament of American Democracy at the present moment • HIGHLY RECOMMENDED
07 January 2021
Fwd: January 6, 2021
Date: Thu, Jan 7, 2021 at 12:55 AM
Subject: January 6, 2021
Today the Confederate flag flew in the United States Capitol. This morning, results from the Georgia Senatorial runoff elections showed that Democrats Raphael Warnock and Jon Ossoff had beaten their Republican opponents—both incumbents—by more than the threshold that would require a recount. The Senate is now split 50-50 between Republicans and Democrats, so the position of majority leader goes to a Democrat. Mitch McConnell, who has bent the government to his will since he took over the position of majority leader in 2007, will be replaced. With the Democrats in control of both Congress and the Executive Branch, it is reasonable to expect we will see voting rights legislation, which will doom the current-day Republican Party, depending as it has on voter suppression to stay in power. Trump Republicans and McConnell Republicans had just begun to blame each other for the debacle when Congress began to count the certified electoral votes from the states to establish that Democrat Joe Biden won the 2020 presidential election. The election was not close—Biden won the popular vote by more than 7 million votes and the Electoral College by 306 to 232—but Trump contends that he won the election in a landslide and "fraud" made Biden the winner. Trump has never had a case. His campaign filed and either lost or had dismissed 62 out of 63 lawsuits because it could produce no evidence for any of its wild accusations. Nonetheless, radical lawmakers courted Trump's base by echoing Trump's charges, then tried to argue that the fact voters no longer trusted the vote was reason to contest the certified votes. More than 100 members of the House announced they would object to counting the votes of certain states. About 13 senators, led by Josh Hawley (R-MO) and Ted Cruz (R-TX), agreed to join them. The move would slow down the count as each chamber would have to debate and take a separate vote on whether to accept the state votes, but the objectors never had anywhere near the votes they needed to make their objections stick. So Trump turned to pressuring Vice President Mike Pence, who would preside over the counting, to throw out the Biden votes. On Monday, Trump tweeted that "the Vice President has the power to reject fraudulently chosen electors." This would throw the blame for the loss onto Pence, but the vice president has no constitutional power to do any such thing, and this morning he made that clear in a statement. Trump then tweeted that Pence "didn't have the courage to do what should have been done." It seemed clear that the voting would be heated, but it was also clear that most of the lawmakers opposing the count were posturing to court Trump's base for future elections. Congress would count Biden's win. But Trump had urged his supporters for weeks to descend on Washington, D.C., to stop what he insisted was the stealing of the election. They did so and, this morning, began to congregate near the Capitol, where the counting would take place. As he passed them on the east side of the Capitol, Hawley raised a power fist. In the middle of the day, Trump's lawyer Rudy Giuliani spoke to the crowd, telling them: "Let's have trial by combat." Trump followed, lying that he had won the election and saying "we are going to have to fight much harder." He warned that Pence had better "come through for us, and if he doesn't, that will be a sad day for our country." He warned that Chinese-driven socialists are taking over the country. And he told them to march on Congress to "save our democracy." As rioters took Trump at his word, Congress was counting the votes alphabetically by state. When they got to Arizona, Senator Ted Cruz (R-TX) stood up to echo the rhetoric radicals had been using to discredit the certified votes, saying that public distrust in the election—created out of thin air by Republicans—justified an investigation. Within an hour, a violent mob stormed the Capitol and Cruz, along with the rest of the lawmakers, was rushed to safety (four quick-thinking staffers brought along the electoral ballots, in their ceremonial boxes). As the rioters broke in, police shot and killed one of them: Ashli Babbitt, an Air Force veteran from San Diego, QAnon believer, and staunch Trump supporter. The insurrectionists broke into the Senate chamber, where one was photographed on the dais of the Senate, shirtless and wearing a bull costume that revealed a Ku Klux Klan tattoo on his abdomen. They roamed the Capitol looking for Pence and other lawmakers they considered enemies. Not finding them, they ransacked offices. One rioter photographed himself sitting at House Speaker Nancy Pelosi's desk with his feet on it. They carried with them the Confederate flag. Capitol police provided little obstruction, apparently eager to avoid confrontations that could be used as propaganda on social media. The intruders seemed a little surprised at their success, taking selfies and wandering around like tourists. One stole a lectern. As the White House, the FBI, the Justice Department, and the Department of Homeland Security all remained silent, President-Elect Joe Biden spoke to cameras urging calm and calling on Trump to tell his supporters to go home. But CNN White House Correspondent Kaitlan Collins later reported that she spoke to White House officials who were "genuinely freaked… out" that Trump was "borderline enthusiastic" about the storming of the Capitol because "it meant the certification was being derailed." At 4:17, Trump issued his own video, reiterating his false claims that he had been cheated of victory. Only then did he conclude with: "Go home, we love you, you're very special." Twitter immediately took the video down. By nighttime Trump's Twitter feed seemed to blame his enemies for the violence the president had incited (although the rhythm of the words did not sound to me like Trump's own usual cadence): "These are the things and events that happen when a sacred landslide election victory is so unceremoniously & viciously stripped away from great patriots who have been badly & unfairly treated for so long. Go home with love & in peace. Remember this day forever!" Twitter took down the tweet and banned the president for at least twelve hours for inciting violence; Facebook and Instagram followed suit. As the afternoon wore on, police found two pipe bombs near the headquarters of the Republican National Committee and the Democratic National Committee in Washington, D.C., as well as a truck full of weapons and ammunition, and mobs gathered at statehouses across the country, including in Kansas, Ohio, Minnesota, California, and Georgia. By 5:00, acting Secretary of Defense Christopher Miller issued a statement saying he had conferred with Chairman of the Joint Chiefs of Staff Mark Milley, Vice President Pence, House Speaker Nancy Pelosi (D-CA), Senate Minority Leader Chuck Schumer (D-NY), and Representative Steny Hoyer (D-MD) and had fully activated the D.C. National Guard. He did not mention the president. By late evening, Washington, D.C., police chief Robert J. Contee III announced that at least 52 people had been arrested and 14 law enforcement officers injured. A total of four people died, including one who died of a heart attack and one who tased themself. White House Counsel Pat Cipollone urged people to stay away from Trump to limit their chances of being prosecuted for treason under the Sedition Act. By midnight, four staffers had resigned, as well as Deputy National Security Adviser Matthew Pottinger, with other, higher level officials also talking about leaving. Even Trump adviser Stephen Miller admitted it was a bad day. Quickly, pro-Trump media began to insist that the attack was a false-flag operation of "Antifa," despite the selfies and videos posted by known right-wing agitators, and the fact that Trump had invited, incited, and praised them. Former Secretary of Defense James Mattis laid the blame for today's attack squarely at the feet of Trump himself: "Today's violent assault on our Capitol, and effort to subjugate American democracy by mob rule, was fomented by Mr. Trump. His use of the Presidency to destroy trust in our election and to poison our respect for fellow citizens has been enabled by pseudo political leaders whose names will live in infamy as profiles in cowardice." The attempted coup drew condemnation from all but the radical Trump supporters in government. Former President George W. Bush issued a statement "on insurrection at the Capitol," saying "it is a sickening and heartbreaking sight." "I am appalled by the reckless behavior of some political leaders since the election," he said, and accused such leaders of enflaming the rioters with lies and false hopes. Senator Mitt Romney (R-UT) was more direct: "What happened here today was an insurrection incited by the President of the United States." Across the country tonight are calls for Trump's removal through the 25th amendment, impeachment, or resignation. The Democrats on the House Judiciary Committee have joined the chorus, writing to Pence urging him to invoke the 25th. Angry at Trump's sabotaging of the Georgia elections in addition to the attack on our democracy, prominent Republicans are rumored to be doing the same. At 8:00, heavily armed guards escorted the lawmakers back to the Capitol, thoroughly scrubbed by janitors, where the senators and representatives resumed their counting of the certified votes. The events of the afternoon had broken some of the Republicans away from their determination to challenge the votes. Fourteen Republican senators had announced they would object to counting the certified votes from Arizona; in the evening count the number dropped to six: Cruz (R-TX), Hawley (R-MO), Cindy Hyde-Smith (R-MS), John Kennedy (R-LA), Roger Marshall (R-KS), and Tommy Tuberville (R-AL). In the House, 121 Republicans, more than half the Republican caucus, voted to throw out Biden's electors from Arizona. As in the Senate, they lost when 303 Representatives voted in favor. Six senators and more than half of the House Republicans backed an attempt to overthrow our government, in favor of a man caught on tape just four days ago trying to strong-arm a state election official into falsifying the election results. Today the Confederate flag flew in the United States Capitol. —- |
06 January 2021
An Open Letter to Vice President Elect Kamala Harris and President Elect Joe Biden
02 January 2021
War on the Virus
23 December 2020
19 December 2020
The Biological Universe
- Life first evolved somewhere in the universe not much later than 10 billion years ago. [Arthur restricts himself to the observable universe, a space about 93 billion light years across in all directions with us at the center and containing approximately 2 trillion galaxies; the entire universe is much, much larger and, applying the principles of isotropy and homogeneity on large scales, is presumably all much the same].
- The oldest instance of the origin of life was overwhelmingly likely to have been on a planet in a galaxy at great distance from the Milky Way, just because there are literally something like a trillion candidate galaxies, each containing hundreds of billions of planets, in the observable universe ("OU" for short).
- Since that time, there has been a steady increase in the number of locales where life has originated and thrived for a time, and at least a good proportion of them continue to have life at the present epoch, such that some form of life is now relatively common in the universe.
- QED, the number of planets in the OU with some form of life, mostly limited to microbial life, is many trillions. (Note: every spiral galaxy, and probably many other types of galaxies, as well, have billions to more than a trillion planets, and a typical spiral galaxy like the Milky Way has hundreds of billions of rocky planets situated in the "habitable zone" of their stars where liquid water is possible. The same should be true of most galaxies).
[Arthur includes an additional bullet point, that some systems have more than one inhabited planet; but I regard that as superfluous to the argument]. - Most or all of the life in the universe is chemically based on carbon compounds. (There are many reasons for including this inference, which I consider to be quite ironclad, but I won't go into it here. My own surmise is that you could correctly say "Essentially all". Fortunately, nucleosynthesis in stars results in the production of a good deal of carbon).
- Add-in, not included by Arthur: All, or nearly all, life in the OU has evolved a genetic information recording system that functions analogously to the nucleic acid system that evolved on Earth, although specific details vary considerably.
- Far and away most life in the OU is constructed of cells, although, again, the exact architecture varies considerably.
- Most life-bearing planets in the OU host only microbial life (single cell or small-aggregates of cells).
- A large number (but proportionally fewer) of the life-bearing planets in the OU also host multicellular life.
- At least some proportion of the biospheres that have evolved multicellular life have evolved "complex" multicellular organisms that conduct photosynthesis to utilize light energy directly (similar to Plants and other photosynthesizer macrobiota on Earth, such as "brown algae"); or that assume roles comparable to those of the Fungi and Animal kingdoms in the Earth biosphere (symbionts and parasites).
- On at least some of the biospheres that have evolved such "complex" multicellular "animals," some of them have evolved advanced motility, including analogs to skeletal (including exoskeletal) structure, musculature, nervous systems, and the beginnings of intelligence, in the sense of directed control by a "brain."
- With all intermediate levels occurring in numbers, some portion of the biospheres that have evolved such complex animal life have proceeded to the evolution of human-level intelligence, although exactly how that manifests varies considerably.
- Some portion of human-level intelligent life develops external symbolic manipulation analogous to language, and eventually culture, and then advanced science and technology. This gives organisms the ability to direct their own evolution from this point, at least to an extent.
- Some portion of the technological species develop artificial biohabitats and are no longer confined to the surfaces of their planets of origin. [I would adventure that we are on the cusp of this development, and that there is no guarantee we will proceed to it; presumably frequently in the past and future, beings at this level do not make this transition successfully or never even try, for whatever reason].
- Once at the level of "space-dwelling," most of the technological species proceed to colonize their star systems and later other stars, and to spread the form of life that originated on their planet to vast numbers of other locations in space, including but not limited to planets that did not and might never evolve life on their own, such that over time most of the life in the universe exists elsewhere than the planetary surfaces where it originated.
- There is virtually no natural limit to the expansion of life under the direction and impetus of intelligence; the future of the OU is for life to encompass a greater and greater proportion of the available locations where sustaining life is possible until some saturation level is reached in the distant future. [Comment: even if this development is relatively rare, it is a threshold; once it occurs, it tends to lead to a permanent change in the course of the development life over a very wide region of space, potentially including multiple galaxies before bumping into others similarly situated, because plausible rates of expansion of such extended biospheres entail small fractions of the age of the planets and galaxies in which they originate. So, ultimately, if this phase occurs at all, it will tend to fill all the available space everywhere].
17 December 2020
Wallace Arthur's «The Biological Universe» and the role of human-level intelligence in the future of life in the universe
Red Dwarf stars and the Long Range Future of Life in the Universe
Posted this as an answer to a question, but it might conceivably be of interest to some people on its own.
06 December 2020
The protein coding problem... one of the great conundra of biology... SOLVED
02 December 2020
Sous vide (something other than politics!)
25 November 2020
24 November 2020
Erasmo Acosta on the implications of the Fermi Principle and the future of man
23 November 2020
Some thoughts on whether K stars are more likely to be the energy centers for living worlds than G stars, and some implications
21 November 2020
A pretty bleak picture
"The news today remains Trump's unprecedented attempt to steal an election in which voters chose his opponents, Democratic candidate Joe Biden and his running mate, Senator Kamala Harris, by close to 6 million votes, so far. A close second to that news is that the leadership of the Republican Party is not standing up to the president, but is instead seemingly willing to let him burn down the country to stay in office.
"Never before in our history has a president who has lost by such a convincing amount tried to claw out a win by gaming the system. Biden has not only won the popular vote by more than any challenger of an incumbent since Franklin Delano Roosevelt's win in 1932, but also has won crucial states by large margins. He is ahead by more than 80,000 votes in Pennsylvania, almost 160,000 votes in Michigan, and between 11,000 and 34,000 each in Georgia, Wisconsin, Arizona, and Nevada."

