11 January 2026

Are GLP-1 drugs the next "miracle" drug for older people?

In my lifetime, it seems the percentage of older adults taking first one of several classes of blood pressure drugs, and/or one of the statins, has gone from none in the latter case and very few in the former, to these drugs being very commonly prescribed. Most of the people my age I know are taking one or both. 

Now it really looks like GLP-1 RA drugs (Glucagon-like Peptide-1 Receptor Agonists, a mouthful, like semaglutide (Ozempic, Wegovy; NovoNordisk) and tirzepatide (Mounjaro, Zepbound; Lilly) may be next. And not only, or possibly not even primarily, because of weight loss. See this: https://news.cuanschutz.edu/news-stories/the-underappreciated-benefits-of-glp-1-receptor-agonists?utm_source=chatgpt.com

There is also some evidence that it may mitigate, slow, or even help prevent the onset of neurovascular dementia, including Alzheimer's, although that's an area that requires a lot more study. Oral forms of these drugs are about to appear on the market, and it seems likely that other, better versions with better unwanted side effect profiles, are likely to appear in the relatively near future. The usual pattern with these things is that costs also slowly come down; to some extent they already have. And insurability, right now pretty dismal, usually improves as well. 

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